International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
Model
BLBIO-SCUC

Item specifics

Applicable Industries
Manufacturing Plant, Vaccine
Weight
200 KG
Machinery Capacity
50L, 700L, 2500L, 50000L
Machinery Test Report
Provided
Key Selling Points
Automatic
Marketing Type
Hot Product 2024
Processing
Fermenting Equipment
Processing Types
bacterial yeast cell culture
Voltage
220V/380V
Power
15-70Kw Depends
Fermenter application
Culture bacterial yeast cell
Function
Culture bacterial yeast cell
Volume
50L-1000L
Sterilizatiom
Autoclave or insitu
PH/DO sensor
Mittler or Hamilton

Review

Description

Parameter
Description
Total volume
 5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL, 500KL etc.
Working volume
 30%~70%
Tank
 Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of diameter and height is 1:2.2-2.5
Stirring system
Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
Stir speed: 50~1000rpm/50-400rpm
Sterilization
Manually Sterilize in place(SIP), auto control by program is optional
Clean
Clean in place (CIP) by spray ball + CIP control valves and pipelines
Gas control
 Control by rotor meter, air flow 1 vvm or O2 flow
Feeding
Automatically feeding by peristaltic pump
Anti-foam control
Automatically add antifoam by peristaltic pump
Temperature control
Auto-control, electric heating range: water source add 5ºC to 70ºC 
PH control
PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.
Do control
0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.
Sampling
Sampling valve, can sterilization separately, manual
Harvest
Zero dead zone bottom valve, can sterilization separately, manual/auto
Lid lift system
30L-500L have lid lift system, 700-1000L have human hole.
Innoculation
4 valves group or pin in with flam protection
Pressure
Auto control, BD Germany pressure transmitter
Exhaust
Have condenser before exhaust, control by diagram valve / Proportional control valve.
Control parameters
10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions
Optional configuration
 Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor(Biomass), Printing, Siemens touch screen, Double mechanical seal, 4-Valves-group for feeding, Bottom valve auto discharge, ASME certificate,Batch culture, Seed transfer, etc.
International Technology Cell Culture Bioreactor
PRODUCT RANGE
1, Glass fermenter from mini 0.2L to 40L,
2, Stainless steel fermenter for reasearch-pilot-industry like 2L-500L-5000L-500KL.
3, Relative device: Steam generator, Chiller, Air compressor, Tubular centrifuge, Disc centrifuge, Shaker,etc.
4,International Technology Cell Culture Bioreactor
International Technology Cell Culture Bioreactor
FERMENTER / BIOREACTOR APPLICATION :
1, Animal vaccine production: Avian influenza vaccine, Porcine PRRS vaccine, Foot-and-mouth disease, Rabies vaccine, Mink vaccine, DTP vaccine, Diphtheria vaccine, Tetanus vaccine, etc.

2, Human vaccine production: Diphtheria vaccine, Diphtheria vaccine, Tetanus vaccine, Meningitis vaccine, Pneumonia IV vaccine, Hepatitis B vaccine, etc.

3, Culture for microorganism (bacterial,fungi,yeast.etc), mammalian cell, plant cell, algae, enzyme, protein, additives, antibiotics etc.
International Technology Cell Culture Bioreactor
International Technology Cell Culture Bioreactor