International Technology Cell Culture Bioreactor Mammalian fermentation basic principles
- Model
- BLBIO-SCUC
Item specifics
- Applicable Industries
- Manufacturing Plant, Vaccine
- Weight
- 200 KG
- Machinery Capacity
- 50L, 700L, 2500L, 50000L
- Machinery Test Report
- Provided
- Key Selling Points
- Automatic
- Marketing Type
- Hot Product 2024
- Processing
- Fermenting Equipment
- Processing Types
- bacterial yeast cell culture
- Voltage
- 220V/380V
- Power
- 15-70Kw Depends
- Fermenter application
- Culture bacterial yeast cell
- Function
- Culture bacterial yeast cell
- Volume
- 50L-1000L
- Sterilizatiom
- Autoclave or insitu
- PH/DO sensor
- Mittler or Hamilton
Review
Description
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Parameter
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Description
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Total volume
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5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL, 500KL etc.
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Working volume
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30%~70%
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Tank
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Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of diameter and height is 1:2.2-2.5
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Stirring system
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Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
Stir speed: 50~1000rpm/50-400rpm |
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Sterilization
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Manually Sterilize in place(SIP), auto control by program is optional
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Clean
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Clean in place (CIP) by spray ball + CIP control valves and pipelines
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Gas control
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Control by rotor meter, air flow 1 vvm or O2 flow
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Feeding
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Automatically feeding by peristaltic pump
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Anti-foam control
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Automatically add antifoam by peristaltic pump
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Temperature control
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Auto-control, electric heating range: water source add 5ºC to 70ºC
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PH control
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PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.
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Do control
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0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.
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Sampling
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Sampling valve, can sterilization separately, manual
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Harvest
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Zero dead zone bottom valve, can sterilization separately, manual/auto
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Lid lift system
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30L-500L have lid lift system, 700-1000L have human hole.
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Innoculation | 4 valves group or pin in with flam protection | ||
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Pressure
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Auto control, BD Germany pressure transmitter
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Exhaust
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Have condenser before exhaust, control by diagram valve / Proportional control valve.
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Control parameters
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10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions
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Optional configuration
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Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor(Biomass), Printing, Siemens touch screen, Double mechanical seal, 4-Valves-group for feeding, Bottom valve auto discharge, ASME certificate,Batch culture, Seed transfer, etc.
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PRODUCT RANGE
1, Glass fermenter from mini 0.2L to 40L,
2, Stainless steel fermenter for reasearch-pilot-industry like 2L-500L-5000L-500KL.
3, Relative device: Steam generator, Chiller, Air compressor, Tubular centrifuge, Disc centrifuge, Shaker,etc.
4,International Technology Cell Culture Bioreactor
FERMENTER / BIOREACTOR APPLICATION :
1, Animal vaccine production: Avian influenza vaccine, Porcine PRRS vaccine, Foot-and-mouth disease, Rabies vaccine, Mink vaccine, DTP vaccine, Diphtheria vaccine, Tetanus vaccine, etc.
2, Human vaccine production: Diphtheria vaccine, Diphtheria vaccine, Tetanus vaccine, Meningitis vaccine, Pneumonia IV vaccine, Hepatitis B vaccine, etc.
3, Culture for microorganism (bacterial,fungi,yeast.etc), mammalian cell, plant cell, algae, enzyme, protein, additives, antibiotics etc.
