Inventory of bottleneck technologies in the biotechnology field between China and the United States!

Gene sequencing technology: BGI Genomics, as a leading global gene sequencing company, has been included in the restricted list by the United States.

The United States may further restrict the export of advanced gene sequencing equipment and related technologies to China, such as the core technology and key components of high-throughput sequencing machines. 

It may also restrict cooperation and exchange of related technologies.

Gene editing technology: such as CRISPR-Cas9 gene editing technology, related technologies, tools, and materials, to prevent cooperation in the clinical application of gene editing technology.

Innovative drug development technology: Restricting the export of new drug development platform technologies, such as key technologies for antibody drug development and core links in cell therapy technology, including target discovery and vector construction for CAR-T cell therapy. 

Restrict the supply of key experimental equipment, reagents, and consumables in the drug development process.

Biopharmaceutical production process: Restricting the export of advanced biopharmaceutical production process technologies, such as optimized design of bioreactors, large-scale cell culture technology, protein purification processes, etc., increases the difficulty for biopharmaceutical companies in improving production processes and increasing production capacity.

Restricting the export of key raw materials, excipients, and intermediates used in biopharmaceutical production affects the stability of biopharmaceutical production and supply.

What are the main differences in synthetic biology between China and the United States?

Access to bioinformatics databases in the field of bioinformatics and big data: Restrictions on access to US bioinformatics databases, such as access to large amounts of genetic sequences, protein structures, and other bioinformatics information in databases such as the National Center for Biotechnology Information (NCBI).

Biological big data analysis technology: restricts the export of advanced biological big data analysis software and algorithms, hinders biopharmaceutical companies from conducting in-depth analysis and utilization of massive biological data, and affects the efficiency and accuracy of drug target discovery, drug design, and other research and development processes.

Comparison of Fermentation Capacity, Fermentation Industry, and Fermentation Technology between China and the United States!

In the field of synthetic biology, synthetic biotechnology restricts the export of key technologies related to synthetic biology, such as gene synthesis, biological chassis construction, metabolic pathway modification, etc., which affects the ability to develop new drugs, bioenergy, and other aspects using synthetic biology technology.

Synthetic biomaterials and equipment: Restrictions on the export of special biomaterials, biological components, and advanced experimental equipment required for synthetic biology research and production, such as specific enzymes, biosensors, microfluidic chips, etc.