6 iconic products of synthetic biology!

Impossible Foods' plant-based meat burger uses Pasteur Pichia pastoris to produce soy hemoglobin, which is added to the meat patties to improve flavor.

Compared with the traditional production method of beef patties, it greatly reduces land use and greenhouse gas emissions, and the product has been sold in many restaurants and grocery stores around the world.

Pharmaceutical product Januvia, a diabetes drug of Merck, reduces blood sugar level by inhibiting the activity of "dipeptidyl peptidase -4 (DPP -4)".

Its molecular structure contains stereospecific amino groups, making chemical synthesis difficult. Using synthetic biology techniques, starting from the transaminase of the genus Arthrobacter, multiple rounds of directed evolution were carried out to optimize enzyme activity under production conditions, achieving efficient production.

Hyaline film Zymerge's polyimide film products have excellent mechanical properties and thermal/chemical stability, and are clear, transparent, flexible, and stable, suitable for flexible electronic products such as foldable smartphones and wearable electronic devices.

The biopolymer fertilizer developed by Proven Nitrogen Fertilizer Pivot Bio uses gene editing to reshape the genome of γ - kv137 Proteobacter, making it the active ingredient in liquid fertilizers and achieving nitrogen fixation.

This effectively reduces the demand for chemical fertilizers without causing nitrogen pollution to groundwater and greenhouse gas emissions.

Kymriah (CAR-T therapy) is the first engineered cell therapy approved by the FDA for the treatment of leukemia.

By isolating the patient's T cells and using genetic engineering techniques to modify them to express tumor chimeric antigen receptors (CARs), they can be reintroduced into the patient's body to kill tumor cells.

Calyno high oil soybean oil, a genetically edited agricultural product, significantly increases the oleic acid content and reduces the linoleic acid content in the oil produced by soybeans through gene editing technology, reducing the problem of rapid degradation of linoleic acid at frying temperatures. 

In addition, the production process of gene editing technology has relatively fewer gene deletions and no DNA recombination, simplifying regulatory review.