The "super strain" code in the field of medical beauty and health, microbial synthesis leads the trend!

As an important chassis strain for industrial fermentation, Escherichia coli is used to produce various medical beauty active ingredients.

For example, genetically engineered Escherichia coli can efficiently synthesize recombinant collagen, which expresses type III collagen with low immunogenicity and high biocompatibility, and is widely used in skin repair and anti-aging products.

In addition, E. coli is also used to synthesize polyphenolic compounds such as salidroside and ferulic acid, which have antioxidant and whitening effects and are added to functional skincare products.

Yeast exhibits outstanding performance in recombinant protein production. Pichia pastoris is used to produce high-purity recombinant humanized type III collagen, with a shake flask yield of over 1g/L and significant industrial fermentation potential.

In addition, yeast can synthesize terpenoids such as squalene and retinol through metabolic engineering, which play important roles in antioxidant and skin metabolism regulation.

In the field of skincare products, lactic acid bacteria regulate the skin's microbiota by secreting lactic acid and antimicrobial peptides, inhibiting harmful bacteria such as Propionibacterium acnes, while promoting stratum corneum renewal and improving skin barrier function.  

 

Oral supplements: Bifidobacterium improves skin health indirectly by regulating gut microbiota, and its metabolites short chain fatty acids (SCFAs) can enhance immune regulation of the gut skin axis and reduce inflammatory reactions.

Traditional botulinum toxin production relies on fermentation and extraction of botulinum toxin, but there is a risk of endotoxin contamination.

The new recombinant technology expresses high-purity botulinum toxin protein through strains such as Escherichia coli, which solves the problem of biosafety from the source and has higher stability and safety.

Bioreactive bacterial strains play a core role in the medical beauty and health industry, driving industry development through technological innovation from basic raw material production to end product applications.

In the future, with the advancement of synthetic biology and precision medicine, the application of bacterial strains will become more efficient, safe, and personalized, providing consumers with higher quality health solutions.